There are more than 150 million men who get affected by Erectile Dysfunction all over the world. And the problem was considered as a sever threat to the sex lives of men before the entry of the first erectile drug Viagra and later came Levitra and Cialis. Cialis came in to the market 6 years after the arrival of Viagra but still it is standing tin the first place today. There must be some reason that it has created such craze in men. And the reason is Tadalafil the vital component of Cialis.
• It comes from the class of PDE type5 inhibitor and does the job of inhibiting the PDE enzyme in the blood during sexual intercourse.
• PDE is an enzyme that is found in bood that kills the levels of cGMP in the blood to prevent dilation of arteries and veins. An enzyme which prevents dilation of blood vessel is not favorable to achieve erection. And so is a need for a drug that inhibits the release of PDE enzyme in the blood during sexual arousal.
• Tadalafil acts within 30 minutes from intake and does not have any effects of food intake on the absorption. After it gets in to the vascular system it gets activated whenever the individual get aroused sexually.
• On activation it sets off to inhibit the enzyme PDE and thus result increased concentration of cGMP and thus facilitates dilation of arteries and when lots of bold flows in to the penis the veins leaving penis are contracted as a result blocking the blood inside penis.
• The trapped blood inside the blood vessel causes pressure and so an erection that is necessary enough to satisfy you sexual desire is attained.